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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL5
All Species:
28.48
Human Site:
T142
Identified Species:
44.76
UniProt:
Q93034
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93034
NP_003469.2
780
90955
T142
V
R
K
L
M
L
D
T
W
N
E
S
I
F
S
Chimpanzee
Pan troglodytes
XP_001137909
721
84087
E123
Q
L
V
I
G
V
R
E
S
Y
V
N
L
C
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546540
811
94684
T173
V
R
K
L
M
L
D
T
W
N
E
S
I
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V5
780
90956
T142
V
R
K
L
M
L
D
T
W
N
E
S
I
F
S
Rat
Rattus norvegicus
Q9JJ31
780
90872
T142
V
R
K
L
M
L
D
T
W
N
E
S
I
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508663
779
91022
T141
V
R
K
L
M
L
D
T
W
N
E
S
I
F
S
Chicken
Gallus gallus
XP_417163
809
94020
T171
V
R
K
L
M
L
D
T
W
N
E
S
I
F
S
Frog
Xenopus laevis
Q6GPF3
768
88937
N134
D
R
V
Y
V
Q
Q
N
N
V
E
N
V
Y
N
Zebra Danio
Brachydanio rerio
XP_001922879
780
90814
T142
V
R
K
L
M
L
D
T
W
N
E
S
I
F
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
Y130
V
L
D
G
I
C
N
Y
L
N
R
N
W
V
K
Honey Bee
Apis mellifera
XP_623958
789
91733
D144
I
V
R
K
L
M
L
D
S
W
N
Q
S
I
F
Nematode Worm
Caenorhab. elegans
Q23639
765
88890
K126
I
R
T
V
M
L
E
K
W
N
E
I
I
F
M
Sea Urchin
Strong. purpuratus
XP_787630
787
91852
M154
D
S
T
V
R
K
L
M
L
E
S
W
S
H
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
P127
I
A
R
R
S
L
P
P
L
N
E
V
G
L
T
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
G146
V
Q
K
E
R
S
D
G
K
R
H
I
F
D
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
95.8
N.A.
98.4
98.7
N.A.
98.8
95.6
27.3
95.1
N.A.
29.7
72.3
51.4
72.9
Protein Similarity:
100
92.4
N.A.
96
N.A.
99.6
99.6
N.A.
99.2
96.1
50.2
98.3
N.A.
51.2
83.4
69.3
84.5
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
100
100
13.3
93.3
N.A.
13.3
0
53.3
0
P-Site Similarity:
100
33.3
N.A.
100
N.A.
100
100
N.A.
100
100
46.6
93.3
N.A.
33.3
26.6
73.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
7
% C
% Asp:
14
0
7
0
0
0
54
7
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
7
0
0
7
7
0
7
67
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
54
7
% F
% Gly:
0
0
0
7
7
0
0
7
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% H
% Ile:
20
0
0
7
7
0
0
0
0
0
0
14
54
7
0
% I
% Lys:
0
0
54
7
0
7
0
7
7
0
0
0
0
0
7
% K
% Leu:
0
14
0
47
7
60
14
0
20
0
0
0
7
7
0
% L
% Met:
0
0
0
0
54
7
0
7
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
7
7
7
67
7
20
0
0
7
% N
% Pro:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% P
% Gln:
7
7
0
0
0
7
7
0
0
0
0
7
0
0
0
% Q
% Arg:
0
60
14
7
14
0
7
0
0
7
7
0
0
0
0
% R
% Ser:
0
7
0
0
7
7
0
0
14
0
7
47
14
0
47
% S
% Thr:
0
0
14
0
0
0
0
47
0
0
0
0
0
0
7
% T
% Val:
60
7
14
14
7
7
0
0
0
7
7
7
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
54
7
0
7
7
0
0
% W
% Tyr:
0
0
0
7
0
0
0
7
0
7
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _